BDBM50268222 CHEMBL4063587

SMILES CCOc1cc(CN2CC3(C2)CC(=NO3)N2CCC(CC2)C(O)=O)cc(OCC)c1-c1ccc(F)cc1

InChI Key InChIKey=UQRAIIGEZLINAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268222   

TargetSomatostatin receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268222(CHEMBL4063587)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO cells assessed as inhibition of SST14-induced forskolin-stimulated intracellular cAMP level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268222(CHEMBL4063587)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO cells assessed as inhibition of SST14-induced forskolin-stimulated intracellular cAMP level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268222(CHEMBL4063587)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO cells assessed as inhibition of SST14-induced forskolin-stimulated intracellular cAMP level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268222(CHEMBL4063587)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO cells assessed as inhibition of SST14-induced forskolin-stimulated intracellular cAMP level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed