BDBM50268983 CHEMBL526841::N-(2-chloro-4-fluorobenzyl)-2,3-dimethyl-6-(1H-1,2,4-triazol-1-yl)imidazo[1,2-a]pyridin-8-amine

SMILES Cc1nc2c(NCc3ccc(F)cc3Cl)cc(cn2c1C)-n1cncn1

InChI Key InChIKey=JMWWMMLEAUJIFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268983   

TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268983(N-(2-chloro-4-fluorobenzyl)-2,3-dimethyl-6-(1H-1,2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268983(N-(2-chloro-4-fluorobenzyl)-2,3-dimethyl-6-(1H-1,2...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268983(N-(2-chloro-4-fluorobenzyl)-2,3-dimethyl-6-(1H-1,2...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed