BDBM50269096 1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-1-yl)ethanone::CHEMBL496080

SMILES CC(C)N1CCC(CC1)Oc1ccc2n(C(C)=O)c(cc2c1)C(=O)N1CCC(F)(F)CC1

InChI Key InChIKey=YQJFPHXEYANWMY-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269096   

TargetHistamine H3 receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50269096(1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isop...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50269096(1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isop...)
Affinity DataEC50:  7nMAssay Description:Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50269096(1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isop...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed