BDBM50269396 CHEMBL4062594

SMILES Nc1nc(Nc2ccc(N3CCN(CC3)C3CC4CCC3C4)c(F)c2)nn1-c1ncnc2ccsc12

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269396   

TargetTyrosine-protein kinase receptor UFO(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50269396(CHEMBL4062594)
Affinity DataEC50:  20nMAssay Description:Inhibition of Axl in human HeLa cells assessed as reduction in AKT phosphorylation at Ser 473 residues pre-incubated for 1 hr before preclustered ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2020
Entry Details Article
PubMed