BDBM50269400 CHEMBL4077272

SMILES COc1ccc2CN(C[C@]3(NC(=O)N(COC(=O)C(C)(C)C)C3=O)c3cc4nc(ccc4o3)-c3cn[nH]c3)C(=O)c2c1F

InChI Key InChIKey=UPMXEMXPKCCWBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269400   

LigandPNGBDBM50269400(CHEMBL4077272)
Affinity DataIC50: 141nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed