BDBM50269785 CHEMBL4064645

SMILES [H][C@@]12CC[C@H](C(=O)Nc3ccccc3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)CC[C@]12C

InChI Key InChIKey=CXCHAQSCCCXEAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269785   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human 5alpha-reductase type2 expressed in baculovirus expression system using [7-3H]T as substrate pretreated for 18 hrs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human 5alpha-reductase type1 expressed in baculovirus expression system using [7-3H]T as substrate pretreated for 18 hrs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50: 2.30E+4nMAssay Description:Displacement of [3H]-DHT from recombinant human androgen receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMed