BDBM50270697 CHEMBL4126092

SMILES CC(=O)c1c(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc2c(C)cc(=O)oc12

InChI Key InChIKey=LQJVAQOUDQLGKX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270697   

Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2020
Entry Details Article
PubMed