BDBM50272070 CHEMBL502803::N-(1-phenylethyl)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine

SMILES CC(Nc1nccc(\C=C\c2c(nc3sccn23)-c2ccccc2)n1)c1ccccc1

InChI Key InChIKey=WKBACBJIPAQRKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272070   

TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272070(N-(1-phenylethyl)-4-(2-(6-phenylimidazo[2,1-b]thia...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272070(N-(1-phenylethyl)-4-(2-(6-phenylimidazo[2,1-b]thia...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272070(N-(1-phenylethyl)-4-(2-(6-phenylimidazo[2,1-b]thia...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed