BDBM50272095 4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfonamide::CHEMBL499068

SMILES COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1

InChI Key InChIKey=XUIMZWHJUVXRFX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50272095   

TargetProstaglandin G/H synthase 2(Human)
Institute of Technology and Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272095BDBM50272095(4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Technology and Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272095BDBM50272095(4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50272095BDBM50272095(4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...)
Affinity DataIC50: 0.00603nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
Institute of Technology and Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272095BDBM50272095(4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...)
Affinity DataIC50: 6nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272095BDBM50272095(4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed