BDBM50272101 (E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[2,1-b]thiazole::CHEMBL505610

SMILES C(=C/c1ccncn1)\c1c(nc2sccn12)-c1ccccc1

InChI Key InChIKey=MRJKXXDKYLGLRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272101   

TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272101((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272101((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272101((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed