BDBM50272131 3-(4-fluorophenyl)-2-(4-(methylsulfonyl)phenyl)-1H-indole::CHEMBL501208
SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]c2ccccc2c1-c1ccc(F)cc1
InChI Key InChIKey=QQNWTSVELIVSMY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50272131
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Technology And Science
Curated by ChEMBL
Institute Of Technology And Science
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Technology And Science
Curated by ChEMBL
Institute Of Technology And Science
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant COX2 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophageMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ovine COX1 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Technology And Science
Curated by ChEMBL
Institute Of Technology And Science
Curated by ChEMBL