BDBM50272159 (E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-4-amine::CHEMBL502543

SMILES Nc1cc(\C=C\c2c(nc3sccn23)-c2ccccc2)ncn1

InChI Key InChIKey=FIZQADVSPVFTQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272159   

TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272159((E/Z)-6-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vin...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed