BDBM50272217 (E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vinyl)pyrimidin-2-amine::CHEMBL526925

SMILES Cn1cnc(c1\C=C\c1ccnc(N)n1)-c1ccccc1

InChI Key InChIKey=ZOBMEONPYSLCBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272217   

TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Tie2 autophosphorylation expressed in CHOK1 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272217((E/Z)-4-(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed