BDBM50272666 (R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-(methylamino)-2-phenylethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-fluorophenoxy)pentanoic acid::CHEMBL451916

SMILES CN[C@@H](Cn1c(=O)c(c(C)n(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1cccc(OCCCCC(O)=O)c1F)c1ccccc1

InChI Key InChIKey=PCOIOMHQQCRCRU-SANMLTNESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272666   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272666((R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-6...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]Pro-N-Et-GnRH from human cloned GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272666((R)-5-(3-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-6...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by microtiter plate-based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed