BDBM50272703 4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methyl-5-(pentan-3-yloxy)pyrimidine::CHEMBL497652

SMILES CCC(CC)Oc1c(C)nc(nc1OC)-c1c(C)cc(C)cc1OC

InChI Key InChIKey=VYZXTZFDEJNWEW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272703   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272703(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272703(4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methy...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed