BDBM50272800 CHEMBL498521::N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-butyl-N-methylbiphenyl-4-carboxamide

SMILES CN(CCc1c[nH]c2ccccc12)C(=O)c1ccc(cc1)-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=BOMNPQYWOQZREH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272800   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272800(N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-butyl-N-methylb...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272800(N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-butyl-N-methylb...)
Affinity DataIC50: 7.45E+5nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed