BDBM50272850 2-(methoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL497650

SMILES COCc1nc(Nc2ccc(cc2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F

InChI Key InChIKey=AUMMEWJHZYQLQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272850   

LigandPNGBDBM50272850(2-(methoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at rat TRPV1 receptor assessed as inhibition of low pH-induced activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50272850(2-(methoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50272850(2-(methoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed