BDBM50272851 2-(ethoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL498666

SMILES CCOCc1nc(Nc2ccc(cc2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F

InChI Key InChIKey=QERUDLNIHPVYAZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272851   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50272851(2-(ethoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-(...)Copy SMILESCopy InChI

Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL