BDBM50273086 2-(pyrrolidin-1-ylmethyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL457843

SMILES FC(F)(F)c1ccc(Nc2nc(CN3CCCC3)nc3cc(ccc23)-c2ncccc2C(F)(F)F)cc1

InChI Key InChIKey=NDJHQUKVEXFVED-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273086   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50273086(2-(pyrrolidin-1-ylmethyl)-N-(4-(trifluoromethyl)ph...)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL