BDBM50273124 2-(2-(4-methylpiperazin-1-yl)ethyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL514248

SMILES CN1CCN(CCc2nc(Nc3ccc(cc3)C(F)(F)F)c3ccc(cc3n2)-c2ncccc2C(F)(F)F)CC1

InChI Key InChIKey=OWLLSGFJYYCLLN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273124   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50273124(2-(2-(4-methylpiperazin-1-yl)ethyl)-N-(4-(trifluor...)Copy SMILESCopy InChI

Affinity DataIC50: 69nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
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