BDBM50273213 2-(((2S,6R)-2,6-dimethylmorpholino)methyl)-7-(3-(trifluoromethyl)pyridin-2-yl)-N-(5-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL457003

SMILES C[C@H]1CN(Cc2nc(Nc3ccc(cn3)C(F)(F)F)c3ccc(cc3n2)-c2ncccc2C(F)(F)F)C[C@@H](C)O1

InChI Key InChIKey=MSKQELXBLADADB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273213   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50273213(2-(((2S,6R)-2,6-dimethylmorpholino)methyl)-7-(3-(t...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL