BDBM50273381 (1R,2S,3S,5R)-methyl 3-(4-ethoxyphenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate hydrochloride::CHEMBL458488

SMILES CCOc1ccc(cc1)[C@H]1C[C@H]2CC[C@H]([C@H]1C(=O)OC)N2C

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273381   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273381((1R,2S,3S,5R)-methyl 3-(4-ethoxyphenyl)-8-methyl-8...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273381((1R,2S,3S,5R)-methyl 3-(4-ethoxyphenyl)-8-methyl-8...)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273381((1R,2S,3S,5R)-methyl 3-(4-ethoxyphenyl)-8-methyl-8...)
Affinity DataKi:  1.69E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed