BDBM50273382 (1R,2S,3S,5R)-methyl 3-(3-fluoro-4-methoxyphenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate hydrochloride::CHEMBL458072

SMILES COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@@H]1c1ccc(OC)c(F)c1)N2C

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273382   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273382((1R,2S,3S,5R)-methyl 3-(3-fluoro-4-methoxyphenyl)-...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273382((1R,2S,3S,5R)-methyl 3-(3-fluoro-4-methoxyphenyl)-...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50273382((1R,2S,3S,5R)-methyl 3-(3-fluoro-4-methoxyphenyl)-...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed