BDBM50273387 4-[1-[3-Chloro-4-[N'-(4-fluoro-2-methylphenyl)-ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid::CHEMBL515348

SMILES Cc1cc(F)ccc1NC(=O)Nc1ccc(CC(=O)N2C[C@@H](F)C[C@H]2COc2ccc(cc2)C(O)=O)cc1Cl

InChI Key InChIKey=IXKJOSLEQCGVAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273387   

TargetIntegrin alpha-4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273387(4-[1-[3-Chloro-4-[N'-(4-fluoro-2-methylphenyl)-ure...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273387(4-[1-[3-Chloro-4-[N'-(4-fluoro-2-methylphenyl)-ure...)
Affinity DataIC50: 330nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cells in presence of human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed