BDBM50273424 CHEMBL450721::N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmethyl-DvalinehydroxamicAcid

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)[C@H](C(C)C)C(=O)NO

InChI Key InChIKey=SBTMZMWGVVORIF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50273424   

TargetNeutrophil collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273424(N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273424(N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 62nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273424(N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273424(N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 235nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273424(N-(4-Methoxybenzenesulfonyl)-N-hydroxycarbonylmeth...)
Affinity DataIC50: 353nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed