BDBM50273425 CHEMBL456774::N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-valinehydroxamicAcid

SMILES CC(C)[C@@H](N(CC(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=LKJAZJMUPQPJNA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50273425   

TargetNeutrophil collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273425(N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-v...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273425(N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-v...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273425(N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-v...)
Affinity DataIC50: 28nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273425(N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-v...)
Affinity DataIC50: 236nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50273425(N-(4-Biphenylsulfonyl)-N-hydroxycarbonylmethyl-D-v...)
Affinity DataIC50: 306nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed