BDBM50273705 6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(1H)-one::CHEMBL499007

SMILES COc1cncc(c1)-c1ccc2CC(=O)CCc2c1

InChI Key InChIKey=VMXXQQUNEIDJSC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273705   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 191nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50: 4.54E+4nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed