BDBM50273879 4-[1-[3-Chloro-4-[N'-(2-chlorophenyl)ureido]-6-fluorophenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid::CHEMBL456180

SMILES OC(=O)c1ccc(OC[C@@H]2C[C@H](F)CN2C(=O)Cc2cc(Cl)c(NC(=O)Nc3ccccc3Cl)cc2F)cc1

InChI Key InChIKey=BBJDKAQNUQEOHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273879   

TargetIntegrin alpha-4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273879(4-[1-[3-Chloro-4-[N'-(2-chlorophenyl)ureido]-6-flu...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273879(4-[1-[3-Chloro-4-[N'-(2-chlorophenyl)ureido]-6-flu...)
Affinity DataIC50: 332nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cells in presence of human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed