BDBM50273935 (4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethyl-1H-4,11b-methanobenzofuro[3,2-d]azocine-8-ol::CHEMBL515842

SMILES Oc1cccc2c1O[C@@H]1CC[C@H]3C[C@@]21CCN3CCc1ccccc1

InChI Key InChIKey=QGADLXMTFNOCAX-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273935   

TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]IOXY from human recombinant kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  190nMAssay Description:Displacement of [125I]IOXY from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  3.71E+3nMAssay Description:Displacement of [125I]IOXY from human recombinant delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273935((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed