BDBM50274354 CHEMBL484357::N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-1-yl]-4-aminobutyl]-4-biphenylcarboxamide

SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCC(=CC1)C#Cc1ccccc1

InChI Key InChIKey=YDCWHOYYMICCQD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50274354   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed