BDBM50274407 CHEMBL484202::N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N-(4-ethynylcyclohex-3-en-1-yl)amine

SMILES CCCN(CCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C1CCC(=CC1)C#C

InChI Key InChIKey=GOPCNWYYZCPBLJ-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50274407   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataEC50:  2.60nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataEC50:  3.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  9.50E+3nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed