BDBM50274758 5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide::CHEMBL458806

SMILES COc1cc(Nc2nc(NCC(C)(C)N)n3cc(nc3c2C(N)=O)-c2ccccc2)cc(OC)c1

InChI Key InChIKey=VTOIZTHVLKSUOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274758   

TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274758(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274758(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed