BDBM50274826 (Z)-N-(4-((6-Methyl-3-oxo-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-1(3H)-ylidene)methyl)phenyl)acetamide::CHEMBL511369

SMILES CC(=O)Nc1ccc(\C=C2/OC(=O)c3c2cc(C)[nH]c3=S)cc1

InChI Key InChIKey=IXFINJSPECFIBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274826   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50274826((Z)-N-(4-((6-Methyl-3-oxo-4-thioxo-4,5-dihydrofuro...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed