BDBM50274962 (Z)-1-((5-Methoxybenzofuran-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL457902

SMILES COc1ccc2oc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)cc2c1

InChI Key InChIKey=FHUIYBXDCMLOJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274962   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50274962((Z)-1-((5-Methoxybenzofuran-2-yl)methylene)-6-meth...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed