BDBM50274979 5-(3-butylpyrrolidin-3-yl)-1H-indole::CHEMBL463585

SMILES CCCCC1(CCNC1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=FIIZGBLPZZYXCS-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50274979   

TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataKi:  9nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 9nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 16nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataKi:  16nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataKi:  60nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 90nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed