BDBM50274987 (Z)-1-((6-(Benzyloxy)-5-methoxybenzofuran-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL458985

SMILES COc1cc2cc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)oc2cc1OCc1ccccc1

InChI Key InChIKey=NGHKSALYCWEJLP-JAIQZWGSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274987   

TargetPerforin-1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50274987((Z)-1-((6-(Benzyloxy)-5-methoxybenzofuran-2-yl)met...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed