BDBM50275015 (Z)-1-((6-Methoxy-1H-indol-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL447352

SMILES COc1ccc2cc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)[nH]c2c1

InChI Key InChIKey=FITGBLGSILDAFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275015   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275015((Z)-1-((6-Methoxy-1H-indol-2-yl)methylene)-6-methy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed