BDBM50275057 (Z)-6-Methyl-1-((1-methyl-1H-indol-2-yl)methylene)-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL516833

SMILES Cc1cc2\C(OC(=O)c2c(=S)[nH]1)=C\c1cc2ccccc2n1C

InChI Key InChIKey=LMZADIIWENOLSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275057   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275057((Z)-6-Methyl-1-((1-methyl-1H-indol-2-yl)methylene)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed