BDBM50275105 CHEMBL4127286

SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#C

InChI Key InChIKey=KQARSQCZYMDXJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275105   

TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275105(CHEMBL4127286)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1-alpha (556 to 574 residues) as substrate after 60 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275105(CHEMBL4127286)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed