BDBM50275276 (Z)-1-((1H-Imidazol-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL486535

SMILES Cc1cc2\C(OC(=O)c2c(=S)[nH]1)=C\c1ncc[nH]1

InChI Key InChIKey=MPFGXCBILYZLOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275276   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275276((Z)-1-((1H-Imidazol-2-yl)methylene)-6-methyl-4-thi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed