BDBM50275314 (Z)-6-Methyl-1-(4-methylbenzylidene)-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL488393

SMILES Cc1ccc(\C=C2/OC(=O)c3c2cc(C)[nH]c3=S)cc1

InChI Key InChIKey=JSXCUZINASZNGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275314   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275314((Z)-6-Methyl-1-(4-methylbenzylidene)-4-thioxo-4,5-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed