BDBM50275378 3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine::CHEMBL487763

SMILES CNCCC(c1c[nH]c2ccccc12)c1ccccc1

InChI Key InChIKey=HYXMIUGYZHSSJS-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275378   

TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataKi:  9nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataKi:  89nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataKi: >1.40E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed