BDBM50275441 5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL486538

SMILES C(c1ccccc1)C1(CCNC1)c1cnc2[nH]ccc2c1

InChI Key InChIKey=DQMQNSKBKIYETN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275441   

TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275441(5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKi:  41nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275441(5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKi:  41nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275441(5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKi:  741nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275441(5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyrid...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed