BDBM50275676 2,2,2-trifluoro-1-(2-(indoline-1-carbonyl)thiazol-5-yl)ethanone::CHEMBL487347

SMILES FC(F)(F)C(=O)c1cnc(s1)C(=O)N1CCc2ccccc12

InChI Key InChIKey=CXLHFLUJPHMEHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275676   

TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50275676(2,2,2-trifluoro-1-(2-(indoline-1-carbonyl)thiazol-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC6 purified from HEK293 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50275676(2,2,2-trifluoro-1-(2-(indoline-1-carbonyl)thiazol-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HDAC1 purified from HEK293 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed