BDBM50275757 4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile::CHEMBL486371

SMILES CN1CCN(CCCOc2cc3ncc(C#N)c(Nc4ccc5nc(N)sc5c4)c3cc2C)CC1

InChI Key InChIKey=HMGYAOFKBQVVQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275757   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275757(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3...)
Affinity DataIC50: 50.6nMAssay Description:Inhibition of cSrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275757(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3...)
Affinity DataIC50: 3.71E+4nMAssay Description:Inhibition of iNOS in mouse ANA1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed