BDBM50275772 CHEMBL471002::N-Allyl-N-ethyl(1R,2R)-2-(Aminomethyl)-1-(2-thienyl)cyclopropanecarboxamide

SMILES CCN(CC=C)C(=O)[C@]1(C[C@H]1CN)c1cccs1

InChI Key InChIKey=VXBRIAOTINONRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275772   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275772(N-Allyl-N-ethyl(1R,2R)-2-(Aminomethyl)-1-(2-thieny...)
Affinity DataIC50: 15nMAssay Description:Displacement of Levo[ring-2,5,6-3H]norepinephrine from human cloned NET expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275772(N-Allyl-N-ethyl(1R,2R)-2-(Aminomethyl)-1-(2-thieny...)
Affinity DataIC50: 140nMAssay Description:Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from human cloned SERT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275772(N-Allyl-N-ethyl(1R,2R)-2-(Aminomethyl)-1-(2-thieny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from human cloned DAT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed