BDBM50275775 CHEMBL469947::N-Allyl-N-cyclopropyl (1R,2R)-2-(Aminomethyl)-1-(2-thienyl)-cyclopropanecarboxamide

SMILES NC[C@@H]1C[C@@]1(C(=O)N(CC=C)C1CC1)c1cccs1

InChI Key InChIKey=OZOIMHBDGJFSOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275775   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275775(N-Allyl-N-cyclopropyl (1R,2R)-2-(Aminomethyl)-1-(2...)
Affinity DataIC50: 17nMAssay Description:Displacement of Levo[ring-2,5,6-3H]norepinephrine from human cloned NET expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275775(N-Allyl-N-cyclopropyl (1R,2R)-2-(Aminomethyl)-1-(2...)
Affinity DataIC50: 45nMAssay Description:Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from human cloned SERT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275775(N-Allyl-N-cyclopropyl (1R,2R)-2-(Aminomethyl)-1-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50275775(N-Allyl-N-cyclopropyl (1R,2R)-2-(Aminomethyl)-1-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from human cloned DAT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed