BDBM50275945 (1R,2R,4R,7bR,9R,11aR)-2,5,5,9,12,12-Hexamethyl-1,3,4,4a,5,8,9,10,11,11a,12,14b-dodecahydro-2H,7bH-benzo[c]isochromeno[3,4-g]chromene-7,14-dione::CHEMBL513403

SMILES C[C@@H]1CC[C@@H]2[C@@H](C1)C1=C(OC2(C)C)C(=O)C2=C(OC(C)(C)[C@@H]3CC[C@@H](C)C[C@@H]23)C1=O

InChI Key InChIKey=PREXAGWWLAMIAK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275945   

TargetATP-dependent translocase ABCB1(Human)
Instituto Universitario De Bio-OrgáNica Antonio GonzáLez

Curated by ChEMBL
LigandPNGBDBM50275945((1R,2R,4R,7bR,9R,11aR)-2,5,5,9,12,12-Hexamethyl-1,...)
Affinity DataKi:  770nMAssay Description:Inhibition of human MDR1 overexpressed in mouse NIH/3T3 cells assessed as daunorubicin accumulation by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed