BDBM50276184 CHEMBL4127537

SMILES C[C@@H]1CCCN1Cc1cc(ccc1-c1ccccc1)C(=O)Nc1ccc2CCC(=O)N(C)c2c1

InChI Key InChIKey=UVEZHZVGDONTIH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276184   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50276184(CHEMBL4127537)Copy SMILESCopy InChI

Affinity DataIC50: 510nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/22/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetTransient receptor potential cation channel subfamily V member 1(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50276184(CHEMBL4127537)Copy SMILESCopy InChI

Affinity DataIC50: 510nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of resiniferatoxin-induced increase in intracellular Ca2+ levelMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL