BDBM50276291 CHEMBL472464::N-benzyl-N-(1'-(2,6-dimethylbenzoyl)-4'-methyl-1,4'-bipiperidin-4-yl)cyclopropanecarboxamide

SMILES Cc1cccc(C)c1C(=O)N1CCC(C)(CC1)N1CCC(CC1)N(Cc1ccccc1)C(=O)C1CC1

InChI Key InChIKey=PGPNVHBTNHPQAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276291   

TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276291(N-benzyl-N-(1'-(2,6-dimethylbenzoyl)-4'-methyl-1,4...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed